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Slowed Gut Movement. Paralytic ileus is often a variety of ileus exactly where your intestines are not able to go food items as a result of them. Methadone might make this condition even worse.​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​â